Rise Health & Wellness Peptides

BPC-157 (15mg)
$110.00 USD
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Rise Health

BPC-157 is a synthetic pentadecapeptide (15 amino acids) derived from a protective protein found in human gastric juice. It is renowned for its powerful regenerative and healing effects, especially in muscles, tendons, ligaments, nerves, and the gastrointestinal tract. Its systemic healing capabilities, anti-inflammatory effects, and ability to promote angiogenesis have made it widely studied and used in regenerative medicine and sports recovery.

Current Research Focus ▼
  • Muscle, tendon, ligament, and joint healing
  • Post-surgical recovery
  • Wound and skin healing
  • Gut repair (ulcers, leaky gut, IBD, NSAID damage)
  • Nerve regeneration and neuroprotection
  • Anti-inflammatory support (acute and chronic)
  • Vascular protection and angiogenesis support
Mechanism of Action ▼

Angiogenesis Activation: Stimulates VEGF and FGF to promote new blood vessel formation and enhance circulation to injured tissues.

Regulation of Nitric Oxide (NO): Modulates NO pathways to improve vascular tone, tissue oxygenation, and healing responses.

Fibroblast Activation: Increases fibroblast proliferation, leading to improved collagen and extracellular matrix repair.

Inflammatory Pathway Modulation: Lowers TNF-α and IL-6; balances immune response without immunosuppression.

Gastrointestinal Protection: Strengthens mucosal barriers and accelerates healing of intestinal injuries.

Neuroregeneration: Enhances neurotrophic factors and supports neuron survival after oxidative or excitotoxic stress.

Anti-Apoptotic Effects: Promotes cell survival and protects tissues from oxidative or mechanical damage.

Key Research Studies ▼

1. Tendon and Ligament Healing

  • Key findings: Accelerated healing of Achilles tendon injuries in rats; promoted tendon outgrowth without scar formation
  • PMID: 15096699

2. Gastrointestinal Protection

  • Key findings: Protected stomach and intestinal lining from NSAID-induced damage; healed ulcers rapidly
  • PMID: 9403782

3. Muscle and Nerve Regeneration

  • Key findings: Enhanced recovery and reduced nerve damage post-injury
  • PMID: 18492134

4. Wound and Vascular Healing

  • Key findings: Promoted angiogenesis and new blood vessel formation; accelerated tissue healing
  • PMID: 8757844

5. Neuroprotection in Brain Injury

  • Key findings: Reduced brain and spinal cord damage in TBI models; supported regeneration
  • PMID: 21030672
Biological Effects and Benefits
✓
Accelerated Healing:
Speeds up recovery of muscles, tendons, ligaments, and bones. Promotes faster post-surgical or injury recovery.
✓
Gut Health Support:
Helps heal ulcers, leaky gut, and inflammatory bowel conditions such as Crohn’s or colitis. Protects the GI lining from damage caused by NSAIDs, alcohol, or stress.
✓
Anti-Inflammatory Effects:
Reduces inflammation and pain in injured or overused tissues. May support chronic inflammatory conditions.
✓
Joint and Soft Tissue Repair:
Supports cartilage, ligament, and joint healing, making it popular in sports medicine. Can be used locally or systemically for targeted healing.
Biological Effects
✓
Neuroprotective Properties:
Potentially helps with nerve regeneration and protection against brain injury or neurodegeneration.
✓
Cardiovascular and Vessel Protection:
Promotes angiogenesis (formation of new blood vessels), supporting circulation and wound healing. Protects blood vessels from oxidative stress.
✓
Skin and Wound Repair:
Enhances wound healing in burns, cuts, and abrasions. Supports collagen production and regeneration.

Biological Effects and Benefits

Sequence: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val
Molecular Formula: C₆₂H₉₈N₁₆O₂₂
Molecular Weight≈ 1419.5 g/mol (free peptide)

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