Rise Health & Wellness Peptides

TB-500 (10mg)
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Rise Health

TB-500 is a synthetic peptide modeled after Thymosin Beta-4 (Tβ4), a naturally occurring peptide involved in cellular healing and regeneration. TB-500 is designed to promote recovery, reduce inflammation, and support tissue regeneration across muscle, tendon, ligament, and skin systems. It is especially popular in sports medicine and regenerative therapy for its ability to enhance cell migration and angiogenesis.

Current Research Focus

Primary Research Areas:

  • Muscle injury recovery and repair
  • Tendon and ligament healing (tendinitis, strain, post-surgical rehabilitation)
  • Wound healing and post-surgery recovery
  • Inflammation reduction in acute and chronic conditions
  • Hair regrowth support (e.g., alopecia research)
  • Regenerative support in athletic performance and training
Mechanism of Action

1. Actin Regulation: Regulates actin polymerization, improving cellular migration and structural repair processes.

2. Angiogenesis Promotion: Stimulates new capillary formation, enhancing blood flow and nutrient delivery to injured tissues.

3. Fibroblast Activation: Promotes recruitment of fibroblasts to injury sites, supporting extracellular matrix (ECM) remodeling.

4. Inflammation Reduction: Modulates inflammatory responses, allowing faster and less painful tissue recovery.

5. Tissue Regeneration Support: Enhances cellular proliferation and remodeling in muscle, skin, and connective tissues.

Key Research Studies

1. Tissue Regeneration & Angiogenesis

  • Study focus: Cell migration, angiogenesis, and wound healing
  • Key findings: Enhanced blood vessel formation and fibroblast activation
  • PMID: 21883065

2. Wound Healing in Mouse Models

  • Study focus: Effects on cutaneous wound closure
  • Key findings: Accelerated wound healing via increased angiogenesis and tissue regeneration
  • PMID: 16648552

3. Muscle Regeneration

  • Study focus: Repair of injured muscle tissue
  • Key findings: Promoted actin polymerization and muscle cell migration
  • PMID: 24097394

4. Tendon Healing

  • Study focus: Collagen production and tendon recovery
  • Key findings: Enhanced tendon regeneration and reduced recovery time
  • PMID: 23239360

5. Human Application for Chronic Wounds

  • Study focus: Post-surgical and chronic wound healing in humans
  • Key findings: Accelerated healing and improved tissue repair in clinical settings
  • PMID: 20221173
Biological Effects and Benefits
Muscle Recovery and Injury Repair:
Promotes faster recovery from muscle injuries, tears, and strains by accelerating tissue repair and regeneration.
Tendon and Ligament Healing:
Supports healing of tendons and ligaments, enhances collagen formation, and improves recovery time in both acute and chronic injuries.
Wound Healing:
Speeds up recovery of open wounds and surgical incisions, making it beneficial in post-surgical and acute injury settings.
Biological Effects
Anti-Inflammatory Properties:
Helps reduce inflammation, easing pain and discomfort associated with injuries and certain chronic conditions.
Hair Growth Support:
Emerging research suggests it may stimulate hair follicle regeneration and support hair growth in individuals experiencing alopecia.

Biological Effects and Benefits

Sequence: N-Acetyl-Leu-Lys-Lys-Thr-Glu-Thr-Gln (Ac-LKKTETQ)

Molecular Formula= C₂₁₂H₃₅₀N₅₆O₇₈S

Molecular Weight ≈ 4,963.4 g/mol

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