Rise Health & Wellness Peptides

CJC-1295 + DAC (5mg/5mg)
$95.00 USD
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Rise Health

The combination of CJC-1295 and Ipamorelin is a synergistic peptide therapy designed to stimulate the body’s natural production of growth hormone (GH) and insulin-like growth factor 1 (IGF-1). CJC-1295 is a growth hormone-releasing hormone (GHRH) analog with a long half-life, while Ipamorelin is a selective growth hormone-releasing peptide (GHRP) known for its clean hormonal profile, avoiding unwanted spikes in cortisol or prolactin. Together, they enhance fat metabolism, tissue repair, muscle recovery, and overall cellular regeneration.

Current Research Focus ▼

Primary Research Areas:

  • Increased growth hormone and IGF-1 production
  • Fat loss (particularly visceral fat)
  • Muscle tone improvement and faster post-workout recovery
  • Sleep enhancement via natural GH rhythms
  • Skin, joint, and hair health
  • Anti-aging support and cellular regeneration
Mechanism of Action ▼

1. CJC-1295 – GHRH Analog: Binds to GHRH receptors in the pituitary to trigger growth hormone secretion in a rhythmic and extended manner.

2. Ipamorelin – GHRP Mimetic: Activates ghrelin receptors selectively to amplify GH release without significantly affecting cortisol or prolactin levels.

3. Synergistic GH Release: Combined activation of hypothalamic (GHRH) and pituitary (ghrelin) pathways to mimic natural GH cycling and optimize endocrine balance.

Key Research Studies ▼

1. CJC-1295 – GH and IGF-1 Elevation

  • Objective: Assess long-term GH and IGF-1 elevation after a single injection.
  • Findings: 2–3x increase in GH; IGF-1 levels remained elevated for up to 6 days.
  • Published in: Journal of Clinical Endocrinology & Metabolism, 2006.
  • Link: View Study

2. Ipamorelin – Selectivity Study

  • Objective: Compare GH stimulation versus GHRP-2 and GHRH.
  • Findings: Selectively increased GH without affecting cortisol or prolactin.
  • Published in: Journal of Clinical Endocrinology & Metabolism, 1998.
  • Link: Journal Reference

3. Ipamorelin – Summary on Selectivity

  • Title: “Ipamorelin: the first selective GH secretagogue.”
  • Reference: PubMed ID 9931193.
  • Link: View Abstract
Biological Effects and Benefits
✓
Accelerated Fat Loss:
AOD 9604 stimulates lipolysis; GH release from CJC-1295 and Ipamorelin enhances fat metabolism and lean mass preservation.
✓
Body Recomposition:
Simultaneously reduces fat mass and increases lean muscle tone with no water retention.
✓
Enhanced Recovery:
GH elevation supports tissue healing, muscle recovery, and collagen synthesis.
Biological Effects
✓
Non-Diabetogenic:
AOD 9604 does not elevate blood sugar or impair insulin sensitivity.
✓
Improved Skin & Joint Health:
IGF-1 promotes integrity and regeneration of collagen and connective tissues.
✓
Better Sleep & GH Rhythms:
CJC-1295 and Ipamorelin mimic natural GH pulses, enhancing release during sleep.

Biological Effects and Benefits

CJC-1295
Sequence: Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg
Molecular Formula: C₁₅₂H₂₅₂N₄₄O₄₂
Molecular Weight: ~3358.9 g/mol
Ipamorelin
Sequence: Aib-His-D-2-Nal-D-Phe-Lys-NH2
Molecular Formula= C₃₈H₄₉N₉O₅
Molecular Weight= 711.85 g/mol

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