Rise Health & Wellness Peptides

Selank (10mg)
$75.00 USD
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Rise Health

N-Acetyl Selank is a synthetic peptide derived from Selank, which itself is an analogue of the human tuftsin peptide. This acetylated version is designed for enhanced stability and potency, offering nootropic, anxiolytic, and neuroprotective benefits. It modulates key neurotransmitters like serotonin, dopamine, and GABA, and has been researched for its effects on anxiety reduction, mood stabilization, cognitive enhancement, and immune regulation.

Current Research Focus

Primary Research Areas:

  • Anxiety and stress reduction
  • Cognitive enhancement and memory support
  • Mood stabilization
  • Neuroprotection and brain health
  • Immune system modulation
Mechanism of Action

1. Neurotransmitter Regulation: Modulates levels and activity of GABA, serotonin, and dopamine, supporting balanced mood and cognitive clarity.

2. BDNF Interaction: Stimulates neurogenesis and synaptic plasticity through Brain-Derived Neurotrophic Factor (BDNF) signaling pathways.

3. GABA Modulation: Enhances inhibitory neurotransmission, contributing to stress relief and calmness without significant sedation.

4. Cytokine Balance: Reduces pro-inflammatory cytokines while supporting immune resilience and homeostasis.

5. Dopamine Metabolism Support: Helps prevent dopamine depletion, maintaining motivation, energy, and mental sharpness.

Key Research Studies

1. Anxiolytic & Antidepressant Effects

  • Study focus: Anxiety and stress reduction via neurotransmitter modulation
  • Key findings: Demonstrated anxiolytic effects comparable to benzodiazepines in some models without marked sedation or dependency patterns
  • Mechanism observed: Enhanced GABAergic, serotonergic, and dopaminergic signaling
  • Subjects: Rodent models and limited human clinical trials

2. Cognitive & Memory Enhancement

  • Study focus: Learning and memory performance
  • Key findings: Increased BDNF expression and improved synaptic plasticity markers
  • Implication: Potential relevance in age-related cognitive decline and neurodegenerative research

3. Neuroprotective Properties

  • Study focus: Protection against oxidative and inflammatory neural damage
  • Key findings: Reduced pro-inflammatory cytokines and supported neuronal survival
  • Application context: Brain injury and ischemic condition models

4. Immune System Modulation

  • Study focus: Cytokine regulation and immune balance
  • Key findings: Reduced inflammatory markers and supported antiviral immune responses
  • Investigational context: Immune dysregulation and chronic inflammation

5. Dopamine & Reward System Modulation

  • Study focus: Dopamine metabolism and reward behavior
  • Key findings: Improved motivation, focus, and emotional stability markers
  • Implication: Exploratory research relevance in mood and addiction-related disorders
Biological Effects and Benefits
Neurotransmitter Regulation:
Increases the activity of GABA, serotonin, and dopamine to support balanced mood, emotional stability, and cognitive clarity.
BDNF Interaction:
Stimulates neurogenesis and enhances synaptic plasticity through Brain-Derived Neurotrophic Factor (BDNF) activity.
GABA Modulation:
Promotes stress relief and calmness without impairing alertness or cognitive performance.
Biological Effects
Cytokine Balance:
Helps reduce pro-inflammatory cytokines while supporting immune resilience and overall inflammatory balance.
Dopamine Metabolism Support:
Prevents dopamine depletion, helping maintain motivation, energy levels, and mental sharpness.

Biological Effects and Benefits

Molecular Formula: C37H51N9O10

Molecular Weight: ~776.86 g/mol

Peptide Sequence: Acetyl-Thr-Lys-Pro-Arg-Pro-Gly-Pro

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